[Palmar filiform parakeratotic hyperkeratosis without underlying malignancy].
نویسندگان
چکیده
Filiform hyperkeratosis (FH) is a rare entity clinically characterized by keratotic spicules on the palms, soles or other areas of the body surface. Its association with several diseases, including neoplasms, has been extensively discussed but currently it is not considered a well-defined paraneoplastic disorder. We report a 72-year-old patient that referred lesions on both palms of three months duration. The rest of the body surface did not show similar lesions. Complementary exams did not reveal any abnormal findings. The histopathological exam showed parakeratotic columns with a slightly decreased granular layer and a mild dermal inflammatory infiltrate. In the last years different terms have been employed to refer to these hyperkeratotic lesions contributing to the lack of clarity that currently persists. Although FH might be classified close to the clinical spectrum of porokeratoses, it presents particular clinical and histological findings that allow it to be considered a separate entity. We report a new case of this rare disorder with exclusive palmar involvement in a patient without underlying malignancy and review the main characteristics of similar cases reported in the literature. Despite the obscure association between this entity and neoplasms, the majority of authors deem it necessary to rule out underlying diseases.
منابع مشابه
Spiny keratoderma of the palms successfully treated with topical tacalcitol.
Sir, Spiny keratoderma is a rare disease characterized by keratotic spicules resembling a “music box spine” located on the palms and soles (1). This entity has been reported under several different names, such as punctate keratoderma (2), punctate porokeratotic keratoderma (3), palmar filiform hyperkeratosis (4), and spiny keratoderma of the palms and soles (1). We present here a case of spiny ...
متن کاملTegumentary manifestations of Noonan and Noonan-related syndromes
OBJECTIVES Noonan and Noonan-related syndromes are common autosomal dominant disorders with neuro-cardio-facial-cutaneous and developmental involvement. The objective of this article is to describe the most relevant tegumentary findings in a cohort of 41 patients with Noonan or Noonan-related syndromes and to detail certain aspects of the molecular mechanisms underlying ectodermal involvement. ...
متن کاملBilateral Nevoid Hyperkeratosis of the Nipple and/or Areola: A Case Report
Nevoid hyperkeratosis of the nipple and areola (NHNA) is a rare condition, in which the skin of the nipple and/or areola becomes diffusely thickened, hyperpigmented, and covered with filiform or papular warty excrescences. Although it affects both men and woman, approximately 80% of cases ocur in women. Pathogenic mechanisms have been proposed but mainly unsubstantiated. Moreover, specific trea...
متن کاملChondrodermatitis nodularis chronica helicis
© 2017 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow Sir, A 48‐year‐old otherwise healthy man presented with a 3‐year history of a small painful nodule on the right ear. There was aggravation of pain whenever the patient slept in right lateral position. There was no history of trauma. On examination, the free border of the right helix showed a dome‐shaped, firm nodule ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Actas dermo-sifiliograficas
دوره 98 6 شماره
صفحات -
تاریخ انتشار 2007